![]() Verlagsgesellschaft, Leipzig.įernandez, J. Schleip, W., 1936, Ontogenie der Hirudineen, in: Klassen und Ordnungen des Tierreichs, vol. G., and Van Essen, D., 1974, The nervous system of the leech, Sci. 56: 110.ĭeppe, V., Schierenberg, E., Cole, T., Krieg, C., Schmitt, D., Yoder, B., and von Ehrenstein, G., 1978, Cell lineages of the embryo of the nematode Caenorhabditis elegans, Proc. R., 1977, Post-embryonic lineages of the nematode Caenorhabditis elegans, Dey. Le Douarin, N., 1973, A biological cell labeling technique and its use in experimental embryology, Dey. R., 1969, Cell lineage of the imaginal discs in Drosophila gynandromorphs, J. Stern, C., 1968, Genetic Mosaics and Other Essays, Harvard University Press, Cambridge, MA. Mintz, B., 1965, Genetic mosaicism in adult mice of quadriparental lineage, Science 148: 1232. K., 1961, Mouse chimera developed from fused eggs, Nature (London) 190: 857. H., 1929, The claret mutant type of Drosophila simulans: A study of chromosome elimination and cell lineage, Z. This process is experimental and the keywords may be updated as the learning algorithm improves. These keywords were added by machine and not by the authors. As will be seen in this chapter, leeches are well suited for cellular investigations of neuronal development because both their early embryos and their adult nervous systems comprise identifiable cells accessible to experimental manipulation. 2–10 More recently, we have refined and extended Whitman’s century-old cell lineage studies in leech embryos, with particular emphasis on the cellular origins of the leech nervous system. Cell lineage analyses were later extended to the embryos of other species, not only by direct observation but also by use of other techniques, such as selective ablation, application of extracellular marker particles, and, most importantly, production of chimera and genetic mosaics. 1 On the basis of his studies of the development of leeches, Whitman put forward the idea, then quite novel, that each identified cell of the early embryo, and the clone of its descendant cells, plays a specific role in later development. The importance of cell lineage for understanding developmental processes was realized over a century ago by C. One key aspect of the process of neurogenesis at the cellular level is cell lineage, i.e., the embryonic lines of descent of various types of neurons. Once such knowledge is available, specific and well-focused questions can be formulated at the biophysical, biochemical, or genetic levels. To fathom the mechanisms underlying these interactive processes, a detailed knowledge of the course of neurogenesis at the cellular level is essential. The intricate structure and function of the adult nervous system is the result of developmental interactions of factors both intrinsic and extrinsic to the embryonic neurons and their precursor cells. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |